Biophysics and Molecular Materials

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Planar patch-clamp

Adhesion force measurements on cells requires immobilization of the interacting partners to the substrayte and to the force sensor respectively. In a collaboration with nan]i[on, the planar patch-clamp technology turned out to be a perfect platform for AFM experiments with non-adherent cells. The ion conductance of the cell membrane additional becomes accessible with this setup. The complex reaction of a cell to an external stimulus now can be recorded simultaneously with respect to force and to conductance.






Group members:                                 

In cooperation with:
Niels Fertig
Andrea Brüggemann
Dirk Trauner
Steffen Massberg

This research is funded by:
DFG, SFB 863 and SFB 914