Biophysics and Molecular Materials
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POST DOC POSITIONS!

OPEN POST DOC POSITION: Biophysics of Force-Sensing Kinases

Highly motivated candidates with training in biochemistry, biotechnology or biophysics are invited to apply. A background in fluorescence techniques would be advantageous but is not required.

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The relation between force and function steers up modern life sciences. With the development of super-resolution optical and mechanical techniques these systems can be deciphered at the single molecule level.

One main research focus of our team is the investigation of force-sensing proteins and their regulatory role in cell biology. To this end we combine force spectroscopy based on either AFM or magnetic tweezers with super resolution fluorescence techniques (TIRF, FRET, PAINT) to gain detailed insight into the underlying molecular mechanisms.

The successful candidate for this open post doc position will further expand this research towards protein modification/engineering, in vitro expression in micro-fluidics devices and mechano-optics in zero mode waveguides.

The contract will initially be limited to 2 years with the possibility for further extension. Salary is in accordance with the German state regulated public service salary scale TV-L 13. The position is available to date, an early start is appreciated.

Applications including a CV and a short letter of motivation should be sent to

sylvia.kreuzer@physik.uni-muenchen.de

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OPEN POST DOC POSITION: Designer-Cellulosomes by Single Molecule Cut & Paste

Highly motivated candidates with training in physics, physical chemistry, biophysics or bioengineering are invited to apply.

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Biofuel from wood and waste will be a substantial share of our future energy mix and contribute to our organic precursor resources. The hydrocarbons in these materials are tightly packed by lignin. The conversion of lignocellulose to fermentable polysaccharides is the current bottleneck. Up to now, only cellulosomes, the multi-enzyme organelles of bacteria, and certain fungi are capable of breaking down the lignocellulose complexes under ambient conditions; industrial conversion requires harsh and environmentally questionable steps.

In an ERC Advanced Grant project we use single molecule cut and paste technology to assemble large libraries of different designer cellulosomes on a chip surface and combine enzymes from different species produced by on chip in vitro expression. The ultimate goal of this project is to identify the most productive de nuovo arrangement of natural and man-made constituents, which then may be adapted for large-scale production.

The successful candidate for this open post doc position will further expand this
research towards protein modification/engineering, in vitro expression in micro-fluidics
devices and long range single molecule cut & paste assembly.stelle_designer_2

The contract will initially be limited to 2 years with the possibility for further extension.
Salary is in accordance with the German state regulated public service salary scale TV-L 13. The position is available to date, an early start is appreciated.

Applications including a CV and a short letter of motivation should be sent to

sylvia.kreuzer@physik.uni-muenchen.de

Download PDF