Biophysics and Molecular Materials
print


Breadcrumb Navigation


Content
Sarιιsιk Ediz

Dr. Ediz Sarιιsιk

Responsibilities

Cell adhesion
Integrins
bone metastasis, collagen, dentin, tendon
bone marrow derived stem cells
AFM
single cell adhesion force measurements

Contact

Lehrstuhl für Angewandte Physik
und Center for NanoScience
Ludwig-Maximilians-Universität
Amalienstr. 54
80799 München

Room: 006
Phone: +49 (0) 89/ 2180-3133
Fax: +49 (0) 89/ 2180-2050

Education:

  • 2008
    Bachelor, Molecular Biology and Genetics (METU), Ankara, Turkey
  • 2010
    M.Sc., Biology (Biophysics), (METU), Ankara, Turkey
  • 2016
    Dr. hum.biol. Medical Sciences and Biophysics, (LMU), Munich, Germany

Further Information

Publications:

ediz1Decoding Cytoskeleton-Anchored and Non-Anchored Receptors from Single-Cell Adhesion Force Data

Ediz Sariisik, Cvetan Popov, Jochen P. Müller, Denitsa Docheva, Hauke Clausen-Schaumann and Martin Benoit
Biophys J. 2015 Oct 6;109(7):1330-3. doi: 10.1016/j.bpj.2015.07.048

Complementary to parameters established for cell-adhesion force curve analysis, we evaluated the slope before a force step together with the distance from the surface at which the step occurs and visualized the result in a two-dimensional density plot. This new tool allows detachment steps of long membrane tethers to be distinguished from shorter jumplike force steps.... more   PDF

 

 

probingProbing the interaction forces of prostate cancer cells with collagen I and bone marrow derived stem cells on the single cell level.

Sarıısık E, Docheva D, Padula D, Popov C, Opfer J, Schieker M, Clausen-Schaumann H, Benoit M.
Published: March 5, 2013 DOI: 10.1371/journal.pone.0057706, PubMed PMID: 23472100

Adhesion of metastasizing prostate carcinoma cells was quantified for two carcinoma model cell lines LNCaP (lymph node-specific) and PC3 (bone marrow-specific). By time-lapse microscopy and force spectroscopy we found PC3 cells to preferentially adhere to bone marrow-derived mesenchymal stem cells (SCP1 cell line)... more   PDF